Miguel A Perez-Pinzon Selected Research

Protein Kinase C-epsilon

1/2018	Metabolomics Based Identification of SIRT5 and Protein Kinase C Epsilon Regulated Pathways in Brain.
12/2017	Protein kinase C epsilon delays latency until anoxic depolarization through arc expression and GluR2 internalization.
1/2016	Protein Kinase C Epsilon Promotes Cerebral Ischemic Tolerance Via Modulation of Mitochondrial Sirt5.
1/2015	Increased BDNF protein expression after ischemic or PKC epsilon preconditioning promotes electrophysiologic changes that lead to neuroprotection.
5/2011	Signal transducers and activators of transcription: STATs-mediated mitochondrial neuroprotection.
8/2009	Protein kinase C epsilon activation delays neuronal depolarization during cardiac arrest in the euthermic arctic ground squirrel.

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Miguel A Perez-Pinzon Research Topics

Disease

31	Brain Ischemia (Cerebral Ischemia) 07/2019 - 09/2005
21	Ischemia 07/2019 - 12/2007
10	Stroke (Strokes) 01/2022 - 01/2008
8	Heart Arrest (Cardiac Arrest) 01/2015 - 07/2005
5	Infarction (Infarctions) 01/2022 - 02/2014
5	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2022 - 02/2014
5	Hypoglycemia (Reactive Hypoglycemia) 01/2020 - 01/2017
4	Inflammation (Inflammations) 01/2022 - 04/2011
4	Cognitive Dysfunction 01/2020 - 01/2013
4	Alzheimer Disease (Alzheimer's Disease) 07/2019 - 01/2008
4	Brain Injuries (Brain Injury) 01/2018 - 05/2012
2	Acidosis 12/2019 - 01/2018
2	Neurodegenerative Diseases (Neurodegenerative Disease) 07/2019 - 01/2018
2	Mitochondrial Diseases (Mitochondrial Disease) 01/2019 - 05/2011
2	Nervous System Diseases (Neurological Disorders) 11/2017 - 01/2008
2	Reperfusion Injury 12/2012 - 05/2012
2	Amyotrophic Lateral Sclerosis (Lou Gehrig's Disease) 01/2005 - 12/2004
1	Hemorrhage 01/2022
1	Cerebral Hemorrhage 01/2022
1	Hematoma 01/2022
1	Hyperglycemia 01/2020
1	Wounds and Injuries (Trauma) 10/2018
1	Obesity 01/2018
1	Type 2 Diabetes Mellitus (MODY) 01/2018
1	AIDS-Related Complex (ARC) 12/2017
1	Traumatic Brain Injuries (Traumatic Brain Injury) 01/2017
1	Parkinson Disease (Parkinson's Disease) 01/2015
1	Huntington Disease (Huntington's Disease) 01/2015
1	Neurologic Manifestations (Neurological Manifestations) 10/2013
1	Ventricular Fibrillation 10/2013
1	Methemoglobinemia 05/2012
1	Asphyxia (Suffocation) 05/2012
1	Hypotension (Low Blood Pressure) 05/2012
1	Hypoxia (Hypoxemia) 05/2011

Drug/Important Bio-Agent (IBA)

13	Glucose (Dextrose)FDA LinkGeneric 01/2020 - 12/2007
10	Oxygen (Dioxygen)IBA 12/2017 - 12/2007
6	Proteins (Proteins, Gene)FDA Link 10/2018 - 01/2013
6	Protein Kinase C-epsilonIBA 01/2018 - 08/2009
5	Neuroprotective AgentsIBA 06/2019 - 01/2013
5	Sirtuin 1IBA 01/2018 - 01/2008
4	ResveratrolIBA 11/2017 - 01/2008
3	Insulin (Novolin)FDA Link 01/2020 - 01/2018
3	SirtuinsIBA 10/2018 - 04/2011
3	Protein Kinase CIBA 08/2009 - 07/2005
2	Nicotine FDA Link 01/2022 - 04/2018
2	Protein Kinases (Protein Kinase)IBA 07/2019 - 09/2005
2	Adenosine Triphosphate (ATP)IBA 06/2019 - 12/2007
2	NAD (NADH)IBA 10/2018 - 01/2015
2	Estrogen Receptor betaIBA 04/2018 - 02/2016
2	InflammasomesIBA 04/2018 - 02/2016
2	Lactic Acid (Lactate)FDA LinkGeneric 01/2018 - 12/2017
2	Reactive Oxygen Species (Oxygen Radicals)IBA 01/2017 - 06/2015
2	Protein Kinase C-deltaIBA 04/2014 - 01/2011
1	Collagenases (Collagenase)FDA Link 01/2022
1	Streptozocin (Streptozotocin)FDA Link 01/2020
1	Acid Sensing Ion ChannelsIBA 12/2019
1	AcidsIBA 12/2019
1	CalciumIBA 12/2019
1	Ion Channels (Ion Channel)IBA 12/2019
1	Protons (Proton)IBA 12/2019
1	lysyl- arginyl- alanyl- lysyl- alanyl- lysyl- threonyl- threonyl- lysyl- lysyl- arginine (PKCS)IBA 07/2019
1	Phosphotransferases (Kinase)IBA 07/2019
1	Estrogens (Estrogen)FDA Link 01/2019
1	LigandsIBA 01/2019
1	CpG ODN 1826IBA 01/2019
1	erucylphosphocholineIBA 01/2019
1	SolutionsIBA 01/2019
1	Tromethamine (Trometamol)FDA Link 01/2018
1	Facilitative Glucose Transport Proteins (Glucose Transporter)IBA 01/2018
1	AMPA Receptors (AMPA Receptor)IBA 12/2017
1	Brain-Derived Neurotrophic Factor (BDNF)IBA 12/2017
1	Messenger RNA (mRNA)IBA 12/2017
1	Peptide Hydrolases (Proteases)FDA Link 01/2017
1	CytokinesIBA 01/2017
1	ChemokinesIBA 01/2017
1	AntioxidantsIBA 06/2015
1	Transcription Factors (Transcription Factor)IBA 06/2015
1	Nitric Oxide Synthase Type III (Endothelial Nitric Oxide Synthase)IBA 04/2014
1	Vasodilator Agents (Vasodilators)IBA 02/2014
1	methyl palmitateIBA 02/2014
1	stearic acid (magnesium stearate)FDA LinkGeneric 02/2014
1	Fatty Acids (Saturated Fatty Acids)IBA 02/2014
1	EstersIBA 02/2014
1	1-phenyl-1-aminomethylethene (PAME)IBA 02/2014
1	Solutol HS 15IBA 02/2014
1	salicylhydroxamic acid (SHAM)IBA 10/2013
1	Untranslated RNA (Noncoding RNA)IBA 10/2013
1	Histones (Histone)IBA 10/2013
1	Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA 01/2013
1	Estrogen ReceptorsIBA 01/2013
1	NitrogenIBA 12/2012
1	NitritesIBA 05/2012
1	Mitogen-Activated Protein KinasesIBA 05/2011
1	Cytochromes c (Cytochrome c)IBA 01/2011
1	Voltage-Gated Sodium ChannelsIBA 08/2009
1	Adenosine Triphosphatases (ATPase)IBA 08/2009

Therapy/Procedure

21	Therapeutics 01/2022 - 04/2009
1	Induced Heart Arrest (Cardioplegia) 10/2013
1	Estrogen Replacement Therapy 01/2013
1	Resuscitation 05/2012